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Article

Beta-thalassemia microelectronic chip: a fast and accurate method for mutation detection.

Clinical chemistry - 1 Jan 2004

Foglieni Barbara, Cremonesi Laura, Travi Maurizio, Ravani Anna, Giambona Antonino, Rosatelli Maria Cristina, Perra Chiara, Fortina Paolo, Ferrari Maurizio

Abstract excerpt

BACKGROUND: beta-Thalassemia is one of the most common genetic diseases in humans. We developed an automated electronic microchip for fast and reliable detection of the nine most frequent mutations accounting for >95% of the beta-thalassemia alleles in the Mediterranean area. METHODS: We developed a microchip-based assay to identify the nine most frequent mutations (cd39C>T, IVS1-110G>A, IVS1-1G>A, IVS1-6T>C,...

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Identifiers

PMID: 14709638
DOI: 10.1373/clinchem.2003.023077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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