Altered microsatellites in incomplete-type intestinal metaplasia adjacent to primary gastric cancers.

doi:10.1136/jcp.50.10.841

Back to search

Article

Altered microsatellites in incomplete-type intestinal metaplasia adjacent to primary gastric cancers.

Journal of clinical pathology - 1 Oct 1997

Hamamoto T, Yokozaki H, Semba S, Yasui W, Yunotani S, Miyazaki K, Tahara E

Abstract excerpt

AIM: To investigate the presence of genetic instability in precancerous lesions of the stomach. METHODS: Fifteen cases of sporadic gastric cancers with a background of intestinal metaplasia were studied by microsatellite assay at nine loci. Altered metaplastic mucosa was microdissected, reconstru...

Topics

Adenocarcinoma
Autoradiography
Genetic Markers
Humans
Immunohistochemistry
Microsatellite Repeats
Mutation
Precancerous Conditions
Stomach Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.