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Article

Complex clonal mosaicism within microdissected intestinal metaplastic glands without concurrent gastric cancer.

Journal of medical genetics - 1 Sept 2016

Guo Yan, Huang Ayuan, Hu Chuansheng, Zhou Yan, Zhang Xiaodan, Czajkowsky Daniel M, Li Jianfang, Cheng Shidan, Shen Ruizhe, Gu Jianren, Liu Bingya, Shao Zhifeng

Abstract excerpt

BACKGROUND: The transformation of healthy gastric tissue into intestinal metaplasia (IM) is thought to be a critical premalignant step in the development of intestinal-type gastric adenocarcinoma (GA). How such premalignancies contribute to the development of GA is, however, poorly understood. METHODS: In this study, the extent and clonal complexity in IM tissue from patients without gastric cancer were analysed...

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Identifiers

PMID: 27287394
DOI: 10.1136/jmedgenet-2016-103872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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