An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.

doi:10.1158/1055-9965.EPI-06-0918

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Article

An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2007

Schwartzbaum Judith A, Ahlbom Anders, Lönn Stefan, Warholm Margareta, Rannug Agneta, Auvinen Anssi, Christensen Helle Collatz, Henriksson Roger, Johansen Christoffer, Lindholm Carita, Malmer Beatrice, Salminen Tiina, Schoemaker Minouk J, Swerdlow Anthony J, Feychting Maria

Abstract excerpt

BACKGROUND: Glutathione transferases (GST) detoxify environmental and endogenous compounds and levels of two polymorphic GST proteins, GSTM3 and GSTP1, are high in the brain. Previous studies of GSTM3 and GSTP1 polymorphisms and adult brain tumor risk have produced inconsistent results, whereas the GSTM3 -63 variant is newly identified and, therefore, has not yet been studied in this context. We therefore...

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Identifiers

PMID: 17372252
DOI: 10.1158/1055-9965.EPI-06-0918

Genes

GSTM3
GSTP1
NQO1
GSTM1
GSTT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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