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Article

Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3.

Mutation research - 1 Jun 2006

Zhou Jianhua, Shephard Elizabeth A

Abstract excerpt

Flavin-containing monooxygenases (FMOs) catalyze NADPH-dependent monooxygenation of soft-nucleophilic nitrogen, sulfur, and phosphorous atoms contained within various drugs, pesticides, and xenobiotics. Flavin-containing monooxygenase 3 (FMO3) is responsible for the majority of FMO-mediated xenobiotic metabolism in the adult human liver. Mutations in the FMO3 gene can result in defective trimethylamine (TMA)...

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Source

Identifiers

PMID: 16481213
DOI: 10.1016/j.mrrev.2005.09.001

Genes

FMO3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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