Article
A novel approach for the generation of human dendritic cells from blood monocytes in the absence of exogenous factors.
Journal of immunological methods - 1 Jun 2008
Schanen Brian C, Drake Donald R
Abstract excerpt
Human dendritic cells (DCs) for research and clinical applications are typically derived from purified blood monocytes that are cultured in a cocktail of cytokines for a week or more. Because it has been suggested that these cytokine-derived DCs may be deficient in some important immunological functions and might not accurately represent antigen presenting cell (APC) populations found under normal conditions in...
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