Article
[Experimental model of in vitro generation of human dendritic cells].
Pneumologia (Bucharest, Romania) - 1 Jan 2000
Oancea Cristian, Jiga Janina, Tudorache Voicu, Păunescu Virgil, Mihalaş Georgeta, Bunu Carmen, Jiga Lucian
Abstract excerpt
INTRODUCTION: Dendritic cells (DCs) are considered the most powerful antigen-presenting cells (APC) playing a strategic role in triggering the immune response. Monocytes are the physiological precursors of myeloid DCs. AIMS: This paper aims to develop an in vitro experimental model of human dendritic cells generation and phenotypic and functional analysis starting from CD14+ monocyte precursors isolated from...
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