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Article

Exon 19 of EGFR mutation in relation to the CA-repeat polymorphism in intron 1.

Cancer science - 1 Jun 2008

Sueoka-Aragane Naoko, Imai Kazue, Komiya Kazutoshi, Sato Akemi, Tomimasu Rika, Hisatomi Takashi, Sakuragi Toru, Mitsuoka Masahiro, Hayashi Shinichiro, Nakachi Kei, Sueoka Eisaburo

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations in lung cancer enhance tyrosine kinase activity and increase sensitivity to the EGFR tyrosine kinase inhibitor, gefitinib. Mutation analysis of the EGFR gene is therefore indispensable for predicting gefitinib response. We investigated a CA-repeat polymorphism in the EGFR gene related to EGFR mutations. Because an increasing number of CA-repeats at intron 1 of the...

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Identifiers

PMID: 18422739
DOI: 10.1111/j.1349-7006.2008.00804.x
PMCID: PMC11159769

Genes

EGFR
EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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