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Article

A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2008

Marsit Carmen J, Black Candice C, Posner Marshall R, Kelsey Karl T

Abstract excerpt

PURPOSE: The variant allele of CCND1 G870A encodes a splice variant of the cyclin D1 protein, which possesses an increased half-life. To confirm the phenotypic effect of the variant allele, we examined the immunohistochemical staining pattern of the protein in tumors from a case population of head and neck squamous cell carcinoma (HNSCC) and compared it with the genotype of these individuals. We also examined how...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18413827
DOI: 10.1158/1078-0432.CCR-07-4368
PMCID: PMC2640470

Genes

CCND1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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