Article
Association of the A870G cyclin D1 gene polymorphism with genetic susceptibility to nasopharyngeal carcinoma.
Head & neck - 1 Jul 2006
Catarino Raquel J, Breda Eduardo, Coelho Vânia, Pinto Daniela, Sousa Hugo, Lopes Carlos, Medeiros Rui
Abstract excerpt
BACKGROUND: Nasopharyngeal cancer (NPC) is multifactorial, and the genetic background may be a crucial etiologic factor. Cyclin D1 (CCND1) is a key regulator of the cell cycle, and its altered activity is associated with the development of cancer. METHODS: We analyzed the A870G CCND1 polymorphism by polymerase chain reaction/restriction fragment length polymorphism (PCR-RFLP) in 281 individuals, including 94...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
