Association of cyclin D1 polymorphism with increased susceptibility to oral squamous cell carcinoma.

doi:10.1016/j.oraloncology.2004.08.005

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Article

Association of cyclin D1 polymorphism with increased susceptibility to oral squamous cell carcinoma.

Oral oncology - 1 Feb 2005

Holley Sarah L, Matthias Christoph, Jahnke Volker, Fryer Anthony A, Strange Richard C, Hoban Paul R

Abstract excerpt

We have examined the association of the CCND1 A/G870 polymorphism with susceptibility and outcome in 174 German patients with oral SCC (OSCC). The CCND1 G870 allele frequency was increased in cases (G870=0.65) when compared to controls (n=155, G870=0.54) and the distribution of CCND1 genotypes were significantly different (p=0.014). Using logistic regression, correcting for age, gender and tobacco consumption, an...

Topics

Adult
Aged
Carcinoma, Squamous Cell
Cyclin D1
Female
Genetic Predisposition to Disease
Humans
Logistic Models
Male
Middle Aged
Mouth Neoplasms
Polymorphism, Genetic
Risk Factors
Smoking

Source

Open in PubMed

Identifiers

PMID: 15695117
DOI: 10.1016/j.oraloncology.2004.08.005

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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