Article
Association of cyclin D1 polymorphism with increased susceptibility to oral squamous cell carcinoma.
Oral oncology - 1 Feb 2005
Holley Sarah L, Matthias Christoph, Jahnke Volker, Fryer Anthony A, Strange Richard C, Hoban Paul R
Abstract excerpt
We have examined the association of the CCND1 A/G870 polymorphism with susceptibility and outcome in 174 German patients with oral SCC (OSCC). The CCND1 G870 allele frequency was increased in cases (G870=0.65) when compared to controls (n=155, G870=0.54) and the distribution of CCND1 genotypes were significantly different (p=0.014). Using logistic regression, correcting for age, gender and tobacco consumption, an...
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