Article
CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma.
Oral oncology - 1 Jul 2008
Sathyan K M, Nalinakumari K R, Abraham Thomas, Kannan S
Abstract excerpt
Cyclin D1 is an essential regulator of the G1 phase of the cell cycle progression and plays an important role in the transition of the cell from the G1 phase to the S phase of the cell cycle. Overexpression of cyclin D1 is a frequently observed feature of human cancers of diverse histological origin. Recently, we have reported overexpression of cyclin D1 in oral carcinoma. However, the underlying mechanism...
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