Article
Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 1998
Matthias C, Branigan K, Jahnke V, Leder K, Haas J, Heighway J, Jones P W, Strange R C, Fryer A A, Hoban P R
Abstract excerpt
We have examined the correlation of a frequent A/G polymorphism within exon 4 of the cyclin D1 gene (CCND1) with genetic susceptibility and clinical outcome in 384 patients with squamous cell carcinoma (SCC) of the head and neck. CCND1 genotype frequencies were similar in the cases and 191 contro...
Topics
- Adult
- Aged
- Carcinoma, Squamous Cell
- Cyclin D1
- Female
- Genotype
- Head and Neck Neoplasms
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local
