Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals.

Genome research - 1 Jul 2008

Hellmann Ines, Mang Yuan, Gu Zhiping, Li Peter, de la Vega Francisco M, Clark Andrew G, Nielsen Rasmus

Abstract excerpt

We introduce a simple, broadly applicable method for obtaining estimates of nucleotide diversity from genomic shotgun sequencing data. The method takes into account the special nature of these data: random sampling of genomic segments from one or more individuals and a relatively high error rate for individual reads. Applying this method to data from the Celera human genome sequencing and SNP discovery project,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Likelihood Functions

Share to Models, Genetic

Share to Pan troglodytes

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 18411405
DOI: 10.1101/gr.074187.107
PMCID: PMC2493391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals.PMID 18411405Read ↗

Human genome sequence variation and the influence of gene history, mutation and recombination.Semantic proximity Read ↗

Inferring Heterozygosity from Ancient and Low Coverage Genomes.Semantic proximity Read ↗

The Role of Phylogenetically Conserved Elements in Shaping Patterns of Human Genomic Diversity.Semantic proximity Read ↗

A fine-scale chimpanzee genetic map from population sequencing.Semantic proximity Read ↗

Inferring heterozygosity from ancient and low coverage genomesSemantic proximity Read ↗

Why do human diversity levels vary at a megabase scale?Semantic proximity Read ↗

Ubiquitous impact of natural selection on nucleotide diversity in 178 species of primates.Semantic proximity Read ↗

The fine-scale structure of recombination rate variation in the human genome.Semantic proximity Read ↗

A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion.Semantic proximity Read ↗

Heterogeneous distribution of SNPs in the human genome: microsatellites as predictors of nucleotide diversity and divergence.Semantic proximity Read ↗

De novo human genome assemblies reveal spectrum of alternative haplotypes in diverse populations.Semantic proximity Read ↗

Impact and characterization of serial structural variations across humans and great apesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.