Article
Heterogeneous distribution of SNPs in the human genome: microsatellites as predictors of nucleotide diversity and divergence.
Genomics - 1 Mar 2010
Varela Miguel A, Amos William
Abstract excerpt
Understanding the forces that govern the distribution of single nucleotide polymorphisms is vital for many of their applications. Here we conducted a systematic search to quantify how both SNP density and human-chimpanzee divergence vary around different repetitive sequences. We uncovered a highly complicated picture in which these quantities often differ significantly from the genome-wide average in regions...
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