Article
Why do human diversity levels vary at a megabase scale?
Genome research - 1 Sept 2005
Hellmann Ines, Prüfer Kay, Ji Hongkai, Zody Michael C, Pääbo Svante, Ptak Susan E
Abstract excerpt
Levels of diversity vary across the human genome. This variation is caused by two forces: differences in mutation rates and the differential impact of natural selection. Pertinent to the question of the relative importance of these two forces is the observation that both diversity within species and interspecies divergence increase with recombination rates. This suggests that mutation and recombination are either...
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