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Article

The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy.

Cardiovascular research - 1 Aug 2008

Jacques Adam M, Briceno Natalia, Messer Andrew E, Gallon Clare E, Jalilzadeh Shapour, Garcia Edwin, Kikonda-Kanda Gaelle, Goddard Jennifer, Harding Sian E, Watkins Hugh, Esteban M Tomé, Tsang Victor T, McKenna William J, Marston Steven B

Abstract excerpt

AIM: The aim of the study was to compare the functional and structural properties of the motor protein, myosin, and isolated myocyte contractility in heart muscle excised from hypertrophic cardiomyopathy patients by surgical myectomy with explanted failing heart and non-failing donor heart muscle. METHODS: Myosin was isolated and studied using an in vitro motility assay. The distribution of myosin light chain-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18411228
DOI: 10.1093/cvr/cvn094
PMCID: PMC2492731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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