Article
Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy.
PloS one - 1 Jan 2020
Nijenkamp Louise L A M, Bollen Ilse A E, Niessen Hans W M, Dos Remedios Cris G, Michels Michelle, Poggesi Corrado, Ho Carolyn Y, Kuster Diederik W D, van der Velden Jolanda
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is the most frequent genetic cardiac disease with a prevalence of 1:500 to 1:200. While most patients show obstructive HCM and a relatively stable clinical phenotype (stage II), a small group of patients progresses to end-stage HCM (stage IV) within a relatively brief period. Previous research has shown sex-differences in stage II HCM with more diastolic dysfunction in female...
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