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Article

Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin.

The Journal of experimental biology - 1 Jan 2016

Spudich James A, Aksel Tural, Bartholomew Sadie R, Nag Suman, Kawana Masataka, Yu Elizabeth Choe, Sarkar Saswata S, Sung Jongmin, Sommese Ruth F, Sutton Shirley, Cho Carol, Adhikari Arjun S, Taylor Rebecca, Liu Chao, Trivedi Darshan, Ruppel Kathleen M

Abstract excerpt

Hypertrophic cardiomyopathy is the most frequently occurring inherited cardiovascular disease, with a prevalence of more than one in 500 individuals worldwide. Genetically acquired dilated cardiomyopathy is a related disease that is less prevalent. Both are caused by mutations in the genes encoding the fundamental force-generating protein machinery of the cardiac muscle sarcomere, including human β-cardiac...

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Identifiers

PMID: 26792326
DOI: 10.1242/jeb.125930
PMCID: PMC6514469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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