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Article

Environmental tobacco smoke and interleukin 4 polymorphism (C-589T) gene: environment interaction increases risk of wheezing in African-American infants.

The Journal of pediatrics - 1 May 2008

Smith Andrew M, Bernstein David I, LeMasters Grace K, Huey Nanette L, Ericksen Mark, Villareal Manuel, Lockey James, Khurana Hershey Gurjit K

Abstract excerpt

OBJECTIVES: To determine whether infants exposed to environmental tobacco smoke (ETS) having the interleukin 4 (IL-4) or interleukin 13 (IL-13) gene polymorphisms were at increased risk of wheezing. STUDY DESIGN: A birth cohort of 758 infants was evaluated annually by a questionnaire, physical examination, and skin prick testing. DNA samples from 560 children were genotyped for IL-4 C-589T and IL-13 C-1112T. The...

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Identifiers

PMID: 18410779
DOI: 10.1016/j.jpeds.2007.10.011
PMCID: PMC11610233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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