Article
Association of IL-13, RANTES, and leukotriene C4 synthase gene promoter polymorphisms with asthma and/or atopy in African Americans.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000
Moissidis Ioannis, Chinoy Birjis, Yanamandra Krishna, Napper Dawn, Thurmon Theodore, Bocchini Joseph, Bahna Sami L
Abstract excerpt
PURPOSE: IL-13, RANTES (Regulated on Activation, Normal T cells Expressed and Secreted), and cysteinyl leukotrienes are asthma and atopy mediators. Two RANTES -403(G to A) and -28(C to G), an -1055 IL-13(C to T), and a -444(A to C) leukotriene C4 synthase (LTC4S) single nucleotide polymorphisms (SNPs) have been shown in Caucasians and Asians as asthma and atopy risk factors. We studied these SNPs in African...
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