Article
Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study.
The European respiratory journal - 1 Sept 2008
Bottema R W B, Reijmerink N E, Kerkhof M, Koppelman G H, Stelma F F, Gerritsen J, Thijs C, Brunekreef B, van Schayck C P, Postma D S
Abstract excerpt
Studying gene-environment interactions may elucidate the complex origins of atopic diseases but requires large study populations. Pooling data from several cohort studies may help but may also obscure findings. Gene-environment interactions in atopy development were studied and the benefits of pooling data were evaluated. Haplotype-tagging polymorphisms in the genes interleukin (IL)13 and CD14 were genotyped in...
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