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Article

Environmental tobacco smoke and male sex modify the influence of IL-13 genetic variants on cord blood IgE levels.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Aug 2012

Chen Chien-Han, Lee Yungling Leo, Wu Ming-Hsun, Chen Pao-Jen, Wei Tien-Shan, Wu Che-Tsung, Tung Kuan-Yen, Chen Wei J

Abstract excerpt

Elevated cord blood IgE (cIgE) levels enhance the risk of childhood atopic diseases. However, genetic determinants of cIgE elevation and their potential modifiers remain inconclusive. We aimed to investigate the associations of single-nucleotide polymorphisms (SNPs) in the IL-13 gene (IL-13) with cIgE elevation and their interactions with prenatal environmental tobacco smoke (ETS) and neonatal sex. A structured...

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Identifiers

PMID: 22432974
DOI: 10.1111/j.1399-3038.2012.01278.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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