Article
Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians.
Molecular and cellular biochemistry - 1 Jul 2008
Ahluwalia Tarunveer Singh, Ahuja Monica, Rai Taranjit Singh, Kohli Harbir Singh, Sud Kamal, Bhansali Anil, Khullar Madhu
Abstract excerpt
Endothelial dysfunction plays a key role in the pathogenesis of diabetic vascular disease, including diabetic nephropathy. Endothelial-derived nitric oxide synthase (eNOS) gene polymorphisms affect eNOS activity and are associated with endothelial dysfunction. We evaluated the association of the constitutive endothelial nitric oxide synthase gene (eNOS) polymorphisms with type 2 diabetic nephropathy. We genotyped...
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