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Article

Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T>C gene variants with diabetic nephropathy.

Journal of diabetes and its complications - 1 Jan 2000

Ezzidi Intissar, Mtiraoui Nabil, Mohamed Manel Ben Hadj, Mahjoub Touhami, Kacem Maha, Almawi Wassim Y

Abstract excerpt

BACKGROUND: Nitric oxide (NO) produced by endothelial NO synthase (eNOS) mediates a wide range of processes, and abnormal NO production mediated diabetes complications, including diabetic nephropathy (DN). In view of their impact on eNOS activity, polymorphisms in eNOS gene were described as candidates for atherosclerosis and DN. AIMS: We evaluated the association of -786T>C (promoter region), Glu298Asp (Exon 7),...

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Identifiers

PMID: 18413207
DOI: 10.1016/j.jdiacomp.2007.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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