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The association of endothelial nitric oxide synthase (eNOS) gene polymorphisms and diabetic retinopathy among patients with type 2 diabetes: A case-control study.

Molecular vision - 1 Jan 2024

Abu-Hassan Diala W, Al-Bdour Muawyah D, Aolymat Iman, El-Khateeb Mohammed

Abstract excerpt

Purpose: Diabetic patients experience chronic hyperglycemia that increases oxidative stress by enhancing free radical formation and nitric oxide (NO) production. Genetic mutations in the endothelial nitric oxide synthase (eNOS) enzyme gene affect the levels of NO formation. These mutations, together with chronic hyperglycemia, may increase the risk of diabetic retinopathy (DR) development and/or DR progression as...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 39959179
PMCID: PMC11829783

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