Risk association of the nitric oxide synthase VNTR intron 4 a/b variant with diabetic nephropathy - a pilot study.

doi:10.1080/15257770.2024.2317411

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Article

Risk association of the nitric oxide synthase VNTR intron 4 a/b variant with diabetic nephropathy - a pilot study.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2024

Moorthy Swathy, Koshy Teena

Abstract excerpt

Diabetic nephropathy (DN) is known to be a leading complication of type 2 diabetes mellitus (T2D). This study evaluated whether the VNTR intron 4 a/b and rs1799983 polymorphisms of endothelial-derived nitric oxide synthase (eNOS) gene modulated the risk of developing DN in Asian Indian patients. The eNOS variants were genotyped in 200 patients, 100 with DN and 100 without DN. A significant risk association was...

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PMID: 38359337
DOI: 10.1080/15257770.2024.2317411

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