Article
Increased platelet-monocyte aggregation in male claudicants with the Pl(A1/A2) polymorphism of Gp IIb/IIIa.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Aug 2008
McCaslin J, Ashour H, Bhattacharya V, Cleanthis M, Daly A, Stansby G
Abstract excerpt
OBJECTIVES: To investigate the relationship between the Pl(A1/A2) polymorphism and platelet activation and aggregation in patients with Peripheral Arterial Disease (PAD). DESIGN: A prospective single-centre cohort study. METHODS: 45 patients with PAD on aspirin 75mg were recruited and phenotyped/genotyped for the Gp IIb/IIIa Pl(A1/A2) polymorphism. Platelet-Monocyte Aggregation (PMAs) was evaluated using...
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