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Article

The Pl(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients.

Journal of hypertension - 1 Mar 2007

Lanni Francesca, Santulli Gaetano, Izzo Raffaele, Rubattu Speranza, Zanda Bastianina, Volpe Massimo, Iaccarino Guido, Trimarco Bruno

Abstract excerpt

OBJECTIVE: The platelet GPIIIa plays a pivotal role in platelet aggregation. Previous studies showed an association between the GPIIIa Pl(A1/A2) polymorphism and coronary thrombosis, while there is only contrasting evidence about its role in stroke. We explored the possibility that this polymorphism represents a risk factor for stroke in hypertensive patients. METHODS: We studied two populations. In loco, we...

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Identifiers

PMID: 17278970
DOI: 10.1097/HJH.0b013e328013cd67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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