Article
The platelet polymorphism PlA2 is a genetic risk factor for myocardial infarction.
Journal of internal medicine - 1 Jun 2004
Grove E L, Ørntoft T F, Lassen J F, Jensen H K, Kristensen S D
Abstract excerpt
OBJECTIVES: Platelet glycoprotein (GP) receptor IIb/IIIa plays a key role in the development of myocardial infarction (MI), and Pl(A2) is a polymorphism in the gene encoding this receptor. The prevalence of Pl(A2) shows pronounced geographical variation and has to our knowledge not been presented for a Scandinavian population before. Platelets from Pl(A2)-positive individuals show increased aggregability compared...
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