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Article

Overexpression of APP stimulates basal and constitutive exocytosis in PC12 cells.

Neuroscience letters - 9 May 2008

Lee Hye-Won, Park Jeong Won, Sandagsuren Enkh-Undraa, Kim Ki-Bae, Yoo Jin-Ju, Chung Sul-Hee

Abstract excerpt

The mechanisms that underlie the altered neurotransmitter system in Alzheimer's disease (AD) are not well understood. Amyloid precursor protein (APP) is a precursor protein for beta-amyloid, an important trigger protein in the pathogenesis of AD. Duplication of the APP gene as well as APP genes that contain certain mutations has been reported to be associated with familial AD (FAD), and a role of APP in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18395981
DOI: 10.1016/j.neulet.2008.03.038

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Overexpression of APP stimulates basal and constitutive exocytosis in PC12 cells.PMID 18395981Read ↗

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