Article
Overexpression of BACE1 stimulates spontaneous basal secretion in PC12 cells.
Neuroscience letters - 27 Jun 2007
Lee Hye-Won, Seo Hyung-Suk, Ha Ilho, Chung Sul-Hee
Abstract excerpt
Although alterations in the function of the neurotransmitter system have been implicated in the pathology of Alzheimer's disease (AD), the mechanisms that underlie this pathological change are not well understood. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is a key protease in...
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