Article
Interleukin-1beta gene polymorphism associated with radiographic signs of osteoarthritis of the knee.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association - 1 Mar 2008
Kanoh Toshiya, Hasegawa Yukiharu, Masui Tetsuo, Yamaguchi Jin, Ishiguro Naoki, Hamajima Nobuyuki
Abstract excerpt
BACKGROUND: Osteoarthritis is recognized as a noninflammatory, progressive condition, the principal cause of which is regressive changes associated with aging and which pursues a chronic course. Recently, the involvement of genetic factors has been widely reported. The purpose of this study was to identify polymorphisms at particular risk of osteoarthritis of the knee for community-living middle-aged and elderly...
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