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Article

characterization of lepr gene Q223R (RS1137101) genotypes in patients with knee joint osteoarthritis of different radiographic stages.

Wiadomosci lekarskie (Warsaw, Poland : 1960) - 1 Jan 2000

Novoseletskyi Valerii O, Stanislavchuk Mykola A, Shkarupa Volodymyr M, Shvets Liliia V

Abstract excerpt

OBJECTIVE: Introduction: Osteoarthritis is a multifactorial joint disease with a significant role of the genetic factor. The numerous studies have demonstrated that genetic dependence is specific for individual hand, hip and knee regions with a genetic contribution to the pathogenesis of osteoarthrosis varying from 40% to 65%. To assess the role of leptin gene receptor functional activity disturbance in the...

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Source

Identifiers

PMID: 29602931

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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