Article
TotalPlex gene amplification using bulging primers for pharmacogenetic analysis of acute lymphoblastic leukemia.
Molecular and cellular probes - 1 Jun 2008
Kang Hyoung Jin, Oh Yongtaek, Chun Sung-Min, Seo Young Jin, Shin Hee Young, Kim Chul Woo, Ahn Hyo Seop, Han Byoung-Don
Abstract excerpt
Genetic polymorphism among patients with acute lymphoblastic leukemia (ALL) is an important factor in the effectiveness and toxicity of anti-leukemic drugs. Genotyping of various polymorphisms that impact the outcome of anti-leukemic drug therapy (pharmacogenetics) presents an attractive approach for developing individualized therapy. We developed an easy and accurate method of analyzing multiple genes using a...
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