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Article

Polymorphism of the thymidylate synthase gene and risk of relapse in childhood ALL.

Leukemia research - 1 Nov 2011

Pietrzyk Jacek J, Bik-Multanowski Miroslaw, Skoczen Szymon, Kowalczyk Jerzy, Balwierz Walentyna, AlicjaChybicka, Matysiak Michal, Szczepanski Tomasz, Balcerska Anna, Bodalski Jerzy, Krawczuk-Rybak Maryna, Wysocki Mariusz, Sobol Grazyna, Wachowiak Jacek

Abstract excerpt

Polymorphisms of genes encoding proteins involved in drug metabolism can influence the efficacy of leukemia treatment. In this population-wide study we aimed to evaluate selected, metabolically active genetic polymorphisms as prognostic markers of treatment efficacy in acute lymphoblastic leukemia (ALL). A total of 51 cases of leukemia relapse were diagnosed in a group of 354 patients with ALL. A strong...

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Source

Identifiers

PMID: 21550658
DOI: 10.1016/j.leukres.2011.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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