Article
Application of SNaPshot for analysis of thiopurine methyltransferase gene polymorphism.
The Indian journal of medical research - 1 May 2009
Kapoor Gauri, Maitra Arindam, Brahmachari Vani
Abstract excerpt
BACKGROUND & OBJECTIVE: Mercaptopurine, azathioprine, and thioguanine, used as antineoplastic agents and immunosuppressants are catabolized by thiopurine methyltransferase (TPMT) enzyme, which exhibits genetic polymorphism. Genotyping patients and the population to which the patients belong, is i...
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