Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of multiplex PCR method for the analysis of glutathione s-transferase polymorphism.

Molecular diagnosis & therapy - 1 Oct 2011

Kim Min Sun, Kang Hyoung Jin, Park Han Jeong, Yook Yeon-Joo, Han Byoung-Don, Kim Chul Woo, Kim Nam Hee, Lee Ji Won, Kim Hyery, Park Kyung Duk, Shin Hee Young, Ahn Hyo Seop

Abstract excerpt

BACKGROUND: Busulfan is a key compound in myeloablative chemotherapy before hematopoietic stem-cell transplantation in children. Genetic polymorphisms of glutathione S-transferase (GST), which is involved in the metabolism of busulfan, have been implicated in interindividual variability in busulf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glutathione Transferase
Share to GSTA1 gene
Share to GSTM1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GSTP1 gene

Share to GSTT1 gene

Share to Genotype

Share to Multiplex Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 22047155
DOI: 10.1007/BF03256420

Genes

GSTA1
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22047155-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of multiplex PCR method for the analysis of glutathione s-transferase polymorphism.PMID 22047155Read ↗

Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan.Semantic proximity Read ↗

TotalPlex gene amplification using bulging primers for pharmacogenetic analysis of acute lymphoblastic leukemia.Semantic proximity Read ↗

Exploratory analysis of 1936 SNPs in ADME genes for association with busulfan clearance in adult hematopoietic stem cell recipients.Semantic proximity Read ↗

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation.Semantic proximity Read ↗

Rapid determination of common mutations in glutathione S-transferase gene by PCR-based methods in healthy Chinese.Semantic proximity Read ↗

Influence of glutathione S-transferase A1, P1, M1, T1 polymorphisms on oral busulfan pharmacokinetics in children with congenital hemoglobinopathies undergoing hematopoietic stem cell transplantation.Semantic proximity Read ↗

Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients.Semantic proximity Read ↗

Impact of GSTA1 Polymorphisms on Busulfan Oral Clearance in Adult Patients Undergoing Hematopoietic Stem Cell TransplantationSemantic proximity Read ↗

Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning.Semantic proximity Read ↗

Impact of Glutathione S-Transferase Polymorphisms on Busulfan Pharmacokinetics and Outcomes of Hematopoietic Stem Cell Transplantation.Semantic proximity Read ↗

Multiplex PCR-single-base extension genotyping of multiple glutathione S-transferase polymorphisms.Semantic proximity Read ↗

Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and transporters using a customized oligonucleotide array.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.