Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample.

doi:10.1002/ijc.23872

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample.

International journal of cancer - 1 Jan 2009

Schafmayer Clemens, Buch Stephan, Völzke Henry, von Schönfels Witigo, Egberts Jan Hendrik, Schniewind Bodo, Brosch Mario, Ruether Andreas, Franke Andre, Mathiak Micaela, Sipos Bence, Henopp Tobias, Catalcali Jasmin, Hellmig Stephan, ElSharawy Abdou, Katalinic Alexander, Lerch Markus M, John Ulrich, Fölsch Ulrich R, Fändrich Fred, Kalthoff Holger, Schreiber Stefan, Krawczak Michael, Tepel Jürgen, Hampe Jochen

Abstract excerpt

Human chromosome 8q24.21 has been implicated as a susceptibility region for colorectal cancer (CRC) as a result of genome-wide association and candidate gene studies. To assess the impact of molecular variants at 8q24.21 upon the CRC risk of German individuals and to refine the disease-associated region, a total of 2,713 patients with operated CRC (median age at diagnosis: 63 years) were compared with 2,718...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged

Share to Aged, 80 and over

Share to Case-Control Studies

Share to Chromosomes, Human, Pair 8

Share to Colorectal Neoplasms

Share to Germany

Share to Microsatellite Repeats

Source

Open in PubMed

Identifiers

PMID: 18839428
DOI: 10.1002/ijc.23872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample.PMID 18839428Read ↗

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.Semantic proximity Read ↗

Association of 8q24.21 loci with the risk of colorectal cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Genetic variation in 8q24 associated with risk of colorectal cancer.Semantic proximity Read ↗

Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.Semantic proximity Read ↗

Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.Semantic proximity Read ↗

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.Semantic proximity Read ↗

Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.Semantic proximity Read ↗

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.Semantic proximity Read ↗

Cumulative evidence for relationships between multiple variants in 8q24 and colorectal cancer incidence.Semantic proximity Read ↗

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.Semantic proximity Read ↗

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci.Semantic proximity Read ↗

Common variation rs6983267 at 8q24.1 and risk of colorectal adenoma and cancer: evidence based on 31 studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.