Article
Mapping of genetic abnormalities of primary tumours from metastatic CRC by high-resolution SNP arrays.
PloS one - 29 Oct 2010
Sayagués José María, Fontanillo Celia, Abad María del Mar, González-González María, Sarasquete María Eugenia, Chillon Maria del Carmen, Garcia Eva, Bengoechea Oscar, Fonseca Emilio, Gonzalez-Diaz Marcos, De las Rivas Javier, Muñoz-Bellvis Luís, Orfao Alberto
Abstract excerpt
BACKGROUND: For years, the genetics of metastatic colorectal cancer (CRC) have been studied using a variety of techniques. However, most of the approaches employed so far have a relatively limited resolution which hampers detailed characterization of the common recurrent chromosomal breakpoints as well as the identification of small regions carrying genetic changes and the genes involved in them....
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