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Article

Deletion mapping reveals two regions of chromosome 8 allele loss in colorectal carcinomas.

Genes, chromosomes & cancer - 1 May 1994

Yaremko M L, Wasylyshyn M L, Paulus K L, Michelassi F, Westbrook C A

Abstract excerpt

Colorectal carcinogenesis is associated with the accumulation of genetic changes involving both dominant oncogenes and tumor suppressor genes. Although at least four different genes have been implicated in the process, the detection of allele loss from other regions of the genome suggests the involvement of additional genes. The short arm of chromosome 8 is one of these regions; loss of heterozygosity occurs at...

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 8
Colorectal Neoplasms
Heterozygote
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7519868
DOI: 10.1002/gcc.2870100102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7519868-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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