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Article

Family-based association studies for next-generation sequencing.

American journal of human genetics - 8 Jun 2012

Zhu Yun, Xiong Momiao

Abstract excerpt

An individual's disease risk is determined by the compounded action of both common variants, inherited from remote ancestors, that segregated within the population and rare variants, inherited from recent ancestors, that segregated mainly within pedigrees. Next-generation sequencing (NGS) technologies generate high-dimensional data that allow a nearly complete evaluation of genetic variation. Despite their...

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Identifiers

PMID: 22682329
DOI: 10.1016/j.ajhg.2012.04.022
PMCID: PMC3370281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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