Article
Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants.
BMC bioinformatics - 15 Feb 2015
Won Sungho, Kim Wonji, Lee Sungyoung, Lee Young, Sung Joohon, Park Taesung
Abstract excerpt
BACKGROUND: Many disease phenotypes are outcomes of the complicated interplay between multiple genes, and multiple phenotypes are affected by a single or multiple genotypes. Therefore, joint analysis of multiple phenotypes and multiple markers has been considered as an efficient strategy for genome-wide association analysis, and in this work we propose an omnibus family-based association test for the joint...
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