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Article

Altered distribution of beta-catenin and prognostic roles in colorectal carcinogenesis.

Scandinavian journal of gastroenterology - 1 Jan 2008

Chen Senqing, Liu Juying, Li Guimei, Mo Fugen, Xu Xinyu, Zhang Tong, Zhang Xiaomei, Li Jintian, Han Xiao, Sun Yujie

Abstract excerpt

OBJECTIVE: Although beta-catenin cytoplasmic stabilization and nuclear translocation play a key role in initiation of colorectal cancer (CRC), the mechanisms are far from clear. The aim of this study was to investigate the relation of expressions of cyclooxygenase (COX)-2 and E-cadherin, and the beta-catenin gene exon 3 mutation to the altered distribution of beta-catenin, and their roles in CRC progression and...

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PMID: 18365911
DOI: 10.1080/00365520701785194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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