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Article

Beta-catenin and cyclin D1 expression in human hepatocellular carcinoma.

Oncology reports - 1 Jan 2000

Ueta Tsuyoshi, Ikeguchi Masahide, Hirooka Yasuaki, Kaibara Nobuaki, Terada Tadashi

Abstract excerpt

To understand the nature and roles of mutated beta-catenin in human hepatocellular carcinomas (HCCs), 57 cases of surgically resected HCCs were studied. DNAs extracted from each tumor were examined for somatic mutations of exon 3, and the protein expressions of beta-catenin, cyclin D1, and Ki-67 were observed by immunohistochemical staining. beta-catenin mutations in exon 3 were detected in 10 (17.5%) out of 57...

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PMID: 12375019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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