Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.

Cancer - 1 Jul 2001

Wong C M, Fan S T, Ng I O

Abstract excerpt

BACKGROUND: beta-Catenin has been recognized as a critical member of the Wnt signaling pathway, and inappropriate activation of this pathway has been implicated in carcinogenesis. METHODS: To determine the clinical significance of beta-catenin in hepatocellular carcinoma (HCC), we performed mutational analysis at exon 3 of the gene, investigated the subcellular protein expression, and analyzed their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Carcinoma, Hepatocellular
Share to Cytoskeletal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Survival Analysis

Share to Trans-Activators

Source

Identifiers

PMID: 11443619
DOI: 10.1002/1097-0142(20010701)92:1<136::aid-cncr1301>3.0.co;2-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.PMID 11443619Read ↗

Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation.Semantic proximity Read ↗

Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.Semantic proximity Read ↗

Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas.Semantic proximity Read ↗

Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma.Semantic proximity Read ↗

Exploring the Impact of the β-Catenin Mutations in Hepatocellular Carcinoma: An In-Depth Review.Semantic proximity Read ↗

Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma.Semantic proximity Read ↗

Diverse Basis of β-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis.Semantic proximity Read ↗

Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis.Semantic proximity Read ↗

Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.Semantic proximity Read ↗

Beta-catenin and cyclin D1 expression in human hepatocellular carcinoma.Semantic proximity Read ↗

Mutation and overexpression of the beta-catenin gene may play an important role in primary hepatocellular carcinoma among Chinese people.Semantic proximity Read ↗

Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.