Article
Frequent translocalization of beta-catenin in gastric cancers and its relevance to tumor progression.
Oncology reports - 1 Jun 2004
Cheng Xiao-Xin, Sun Yuan, Chen Xiao-Yan, Zhang Kai-Li, Kong Qing-You, Liu Jia, Li Hong
Abstract excerpt
Altered distribution of beta-catenin has been found in many human malignancies including gastric cancer, but its reason(s) and biological implications have not yet been fully clarified. By the methods of frozen tissue array-based immunohistochemistry, RT-PCR and PCR-SSCP followed by DNA sequencing, the patterns of beta-catenin distribution in the subtypes of gastric cancers and their premalignant and...
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