Article
Effects of sex chromosome aneuploidy on male sexual behavior.
Genes, brain, and behavior - 1 Aug 2008
Park J H, Burns-Cusato M, Dominguez-Salazar E, Riggan A, Shetty S, Arnold A P, Rissman E F
Abstract excerpt
Incidence of sex chromosome aneuploidy in men is as high as 1:500. The predominant conditions are an additional Y chromosome (47,XYY) or an additional X chromosome (47,XXY). Behavioral studies using animal models of these conditions are rare. To assess the role of sex chromosome aneuploidy on sexual behavior, we used mice with a spontaneous mutation on the Y chromosome in which the testis-determining gene Sry is...
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