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Article

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 2002

De Vries Geert J, Rissman Emilie F, Simerly Richard B, Yang Liang-Yo, Scordalakes Elka M, Auger Catherine J, Swain Amanda, Lovell-Badge Robin, Burgoyne Paul S, Arnold Arthur P

Abstract excerpt

We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of Sry from the Y and subsequent insertion of an Sry transgene onto an autosome), so that the determination of testis development occurred independently of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12388607
PMCID: PMC6757680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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