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Article

46,XX sex reversal.

Archives of medical research - 1 Jan 2000

Zenteno-Ruiz J C, Kofman-Alfaro S, Méndez J P

Abstract excerpt

In humans, sexual differentiation is directed by SRY, a master regulatory gene located at the Y chromosome. This gene initiates the male pathway or represses the female pathway by regulating the transcription of downstream genes; however, the precise mechanisms by which SRY acts are largely unknown. Moreover, several genes have recently been implicated in the development of the bipotential gonad even before SRY...

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Source

Identifiers

PMID: 11750731
DOI: 10.1016/s0188-4409(01)00322-8

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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